Implantable medical device with adaptive operation

ABSTRACT

An implantable medical device operates with an algorithm that promotes intrinsic conduction and reduces ventricular pacing. The IMD monitors the occurrence of necessary ventricular pacing and takes certain actions based upon whether this occurrence has been relatively high or relatively low. When noise is detected, asynchronous pacing is provided when the occurrence is relatively high and is not provided when relatively low. When atrial threshold testing is performed, the incidence will determine which methodology is utilized.

BACKGROUND

1. Field of the Invention

The present invention relates to medical devices and more specificallyto implantable medical devices.

2. Description of the Related Art

There are a variety of medical devices that sense data, providediagnostic information, and/or deliver therapy. When such a device isimplantable (in whole or in part), it is referred to as an implantablemedical device (IMD). In the present application, IMD refers to devicesthat sense cardiac events and deliver pacing therapy. Such devices mayor may not also include other functions such as defibrillation therapy(e.g., implantable cardioverter defibrillator (ICD)), other monitoringcapabilities, alternate cardiac therapies, or non-cardiac monitoringand/or therapies. Thus, the term pacemaker may be used interchangeablywith IMD in the present context with the understanding that either termmay refer to a device with capabilities beyond those required of apacemaker alone.

Recently, there has been a recognition that intrinsic conduction andventricular depolarization, even if somewhat prolonged, is preferable toventricular pacing; particularly pacing in or near the right ventricularapex. In general, this preference results from the unnatural propagationof a depolarization wavefront that is generated from such a pacing pulse(as compared to intrinsic depolarization).

Previous pacing modes tend to operate at one extreme or another. Forexample, in a true, single chamber AAI/R device, atrial pacing andsensing is possible, but no ability to provide ventricular pacing (orsensing) exists. On the other hand, DDD/R has historically been thedefault selection for dual chamber devices. The DDD/R mode will operateto maintain AV synchrony; however, the AV delay is such that intrinsicconduction is precluded in most cardiac cycles. This results inventricular pacing in a very high percentage of cardiac cycles.

The present assignee has developed new modes that promote intrinsicconduction and are referred to herein generally as ventricular pacingprotocols (VPP). One such VPP is Managed Ventricular Pacing® which iscommercially available. A variety of VPP embodiments have previouslybeen described, for example, as in U.S. Pat. No. 6,772,005, issued Aug.3, 2004, to Casavant et al.; U.S. application Ser. No. 10/246,816, filedSep. 17, 2002; U.S. application Ser. No. 10/755,454, filed Jan. 12,2004; U.S. application Ser. No. 10/850,666, filed May 21, 2004; U.S.application Ser. No. 11/115,605, filed Apr. 27, 2005; U.S. applicationSer. No. 11/096,436, filed Mar. 31, 2005; U.S. application Ser. No.10/814,692, filed Mar. 31, 2004; and U.S. application Ser. No.10/971,686, filed Oct. 25, 2004, which are herein incorporated byreference in their entirety.

As a generalized explanation, a VPP operates in an atrial based pacingmode to promote intrinsic conduction. Ventricular events are sensed andas long as a ventricular event is sensed in a given cardiac cycle (e.g.,A-A interval) the device continues to operate in the atrial based pacingmode. This allows for ventricular sensing during the entire A-Ainterval. Conversely, if there is no ventricular event, the deviceprovides a ventricular backup pace in the subsequent cycle, timed fromthe atrial event (paced or sensed) that initiates this cardiac cycle.Thus, in a VPP it is possible to have an entire cardiac cycle devoid ofventricular activity while ultimately maintaining AV synchrony. Thereare, of course, many variations and embodiments provided that are notdescribed herein for the sake of brevity. It should be appreciated thatoperation in an atrial based pacing mode includes mode switching adevice into such a mode (e.g. AAI/R, ADI/R) and into a mode thatprovides ventricular pacing or alternatively, operation in a complexmode that includes more comprehensive behavior (e.g., FIDDI).

One benefit of the VPP is that the protocol may be initiated withpatients regardless of the status of their AV conduction. Those havingintact or partially intact conduction will benefit in that conduction ispromoted and ventricular pacing is reduced or eliminated. For thosepatients with heart block, the VPP will quickly move to provideventricular pacing and periodically check to determine if conduction hasreturned. Both in initially recognizing the need to pace and performingthe conduction checks, the methodology employed is transparent to thepatient.

As previously indicated physicians implanting a dual chamber deviceoften utilize nominal settings and program the device to DDD/R due toits simplicity. The VPP allows for the same type of comprehensivereliability across patient profiles and without the need to programnumerous parameters upon implant. The VPPs are preferable in that thatthey reduce or minimize ventricular pacing when intact conduction ispresent.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a schematic diagram illustrating an implantable medicaldevice.

FIG. 2 is a flowchart describing one method of selecting a noiseresponse.

FIG. 3 is a table indicating response taken to noise based uponclassification.

FIG. 4 is a flowchart describing one method of selecting a thresholdmeasurement algorithm.

DETAILED DESCRIPTION

FIG. 1 is a schematic illustration of an implantable medical device(IMD) 10 having pacing capabilities. While not illustrated, IMD 10 mayalso include a variety of other monitoring, diagnostic and therapeuticfunctions. Further, FIG. 1 is not meant to comprehensively illustrateall components of an implantable pacemaker.

The IMD 10 includes a housing 12 that contains a microprocessor 14,memory 16, a power supply (e.g., battery) 18, a communication module 20that facilitates telemetry to an external device and a pulse generator22 for generating pacing pulses. A sensor interface 30 is provided tocollect data from one or more sensors/electrodes, one or more of whichmay be disposed on leads 32, 34. The pacing stimuli generated by thepulse generator 22 is deliverable via the leads 32, 34. Also illustratedin FIG. 1 are a VPP module 24, noise detection module 26 and atrialcapture management module 28. It should be appreciated that thesefunctions may be algorithms stored in the memory 16 or incorporated intoother hardware, software, or firmware.

In operation, the IMD 10 senses cardiac events and provides anappropriate response. Most typically, cardiac events are sensed viaelectrodes on the leads 32, 34. These electrodes pick up electricalsignals indicative of specific activities within the heart, typicallyrepresented as an electrogram (EGM) within the device or anelectrocardiogram (ECG) when based upon surface collected data. As iswell known, the cardiac cycle includes an atrial depolarizationrepresented electrically by a P wave, ventricular depolarizationrepresented by the QRS complex, and repolarization represented by a Twave. While sensing algorithms can be relatively complex, in general asensed P wave indicates intrinsic atrial depolarization while a sensed Rwave indicates intrinsic ventricular depolarization. For a given pacingmode, if a P wave or R wave is not sensed within a predetermined timeframe, then the IMD 10 will provide atrial or ventricular pacing withappropriate timing. There are numerous variations to this generalizationsuch as overdrive pacing or various tachycardia pacing therapies. Themain point herein is that the IMD 10 senses data and responds in somefashion to that data.

Though the IMD 10 is implanted within the patient and includes shieldingand various design advancements, it is not immune from electromagneticinterference (EMI) or other types of noise. Common sources of noisewould include physical contact with certain household appliances,vending machines, contact with ungrounded electrical devices (e.g.,swimming pool lights), exposure to certain tracking/security devices,and exposure to medical testing such as an MRI field. Generally, noiseresulting from such exposure is minimal and transient.

Furthermore, the IMD 10 includes the noise detection module 26 toidentify the presence of noise. Thus, when noise is detected the IMD 10will modify its behavior. Each device may take distinct action and eachaction may depend upon the specific noise and/or environment.

As a generalization, the IMD 10 will not consider signals received asvalid cardiac indicators when noise is detected. As such, the IMD 10 isunable to pace (or otherwise act) in response to sensed signals duringthis noise window, since no sensed signal may be deemed reliable. Noiseexposure is typically of a short duration; however, the IMD 10 has noway to determine how long it will last. Thus, the previous response tonoise has been to provide asynchronous pacing during periods of noise.For example, assume a given patient has a right ventricular leadimplanted. When noise is present, the IMD 10 will provide ventricularpacing pulses based upon the best available information (e.g., what rateto pace at, last paced or sensed event) but unsynchronized with respectto any intrinsic atrial or ventricular activity actually occurring. Thisresponse is typically provided regardless of the therapy beingdelivered. That is, if pacing is permitted it will be provided duringthe duration of the noise. In dual chamber devices, this asynchronouspacing is provided in both the atrium and ventricle. This dual chamberpacing will be coordinated (i.e., a pace followed by an appropriate AVIwith a V pace) but is asynchronous with respect to the intrinsic eventsof the heart or any event that otherwise would be sensed absent noise).

FIG. 2 illustrates a noise response of the IMD 10 according to thepresent invention. The IMD 10 operates (100) in a Ventricular PacingProtocol (VPP), such as MVP™. As indicated, the VPP is a mode or modeswitching module that promotes intrinsic conduction and maintains AVsynchrony. A full cardiac cycle is permitted to elapse withoutventricular pacing and a ventricular sense occurring within this windowmaintains operation in this state (deemed to be in an atrial basedmode). If a full cycle elapses without a ventricular sensed event, aventricular pace is delivered at an appropriate time in the immediatelysubsequent cardiac cycle (deemed to be a dual chamber based mode). Thereare number embodiments of VPPs and how they respond subsequently. Insome such embodiments, the device reverts to the atrial based mode afterone cycle with a ventricular pace. Then, if a certain condition is met,the IMD 10 operates in a DDD/R mode for a particular period of time.Such a condition might be if 2 of 4 consecutive cycles lack intrinsicconduction. Once in the DDD/R mode, the IMD 10 will periodically performa conduction check to determine if intrinsic conduction has returned.The initial conduction check occurs a short time after entering themode, e.g., after 1 minute in DDD/R. Subsequent checks (assuming each isunsuccessful) occur after progressively longer durations (e.g., 2, 4, 8,12, 24, 48 minutes, 1, 2, 4, 8 hours etc.). At some point, a longestduration is reached (e.g., 16 or 17 hours) between conduction checks.This assures that a conduction check is performed once per day but atdifferent times of the day. Each conduction check is brief (one to a fewcardiac cycles) and is generally unnoticeable to the patient. Thispermits the VPP to be utilized on any patient; even those with completeheart block. Conversely, when any conduction check is successful, theIMD 10 operates in the atrial based pacing mode and significantlyreduces the occurrence of ventricular pacing, as compared to operationin, e.g., DDD/R over the same time period.

During operation of the IMD 10 the device records (110) data. Oneparameter recorded will relate to the amount of operation in the atrialbased mode as compared to the dual chamber mode and/or operation inDDD/R or a similar traditional mode. The particular type of data mayvary. For example, the IMD 10 may record a percentage of total timeoperated in the atrial based mode, a number of cardiac cycles, apercentage of total cycles operated in the atrial base mode, thenumber/percentage of ventricular pacing pulses delivered over a giventime period or number of cycles, or some suitable alternative.

Based upon this data, the IMD 10 classifies (120) the patient status.For purposes of this description, the patient will be classified ashaving generally intact conduction (intact), complete or almost completeblock (blocked), or intermediate. It should be appreciated that thereare medical classifications/definitions of AV conduction and the terms(intact, blocked, intermediate) are not meant to be defined herein bysuch medical definitions. The parameters used to define these threecategories may be set by the manufacturer or may be selectivelyprogrammed. In practice, the vast majority of patients will be at oneend of the spectrum or the other. That is, there is either a very lowoccurrence of ventricular pacing or a very high occurrence. In oneembodiment, providing ventricular pacing in 20% or less of the relevantcardiac cycles is labeled as intact, 20%-80% is labeled intermediate and80% or greater is labeled blocked. In another embodiment, these valuesare 10%, 10%-90%, and 90% or greater. In yet another embodiment, thepatient is labeled intact if pacing occurs in less than 5% and labeledblocked using either of the two upper limits. Again, the parameters maybe programmed to any value specified. The intermediate category may alsobe eliminated, with the patient defined as either intact or blocked.

It should be appreciated that similar data recording and classificationmay be provided for atrial pacing. That is, with a dual chamber devicehaving atrial pacing capability, the device may provide atrial pacingfrequently or infrequently, depending upon need. By relying upon the SAnode to initiate pacing (when appropriate), the pacing rate is directlycontrolled by physiological conditions as opposed to electromechanicalsurrogates (e.g., an accelerometer). For atrial pacing, theclassifications would be reliable, intermediate (optional), dependant.Reliable would indicate that an intrinsic sinus rhythm is present in anappropriate percentage of cycles. Dependant would indicate that thepatient relies upon atrial pacing in a large percentage of cardiaccycles and intermediate, if used would be the values between. The actualtime or percentages used may be the same as those identified forventricular classifications, or may be set independently and vary.

As operation continues with the VPP, sufficient data is collected toclassify the patient. In addition, the noise detection module 26functions and monitors (130) for noise. If no noise is detected (130),normal operation continues (100). If noise is detected (130), then thenext action taken will depend upon the classification made in step 120.Assuming the patient is labeled as intact (based upon data collectedduring operation of the VPP), then the IMD 10 will inhibit pacing, dueto the previously recorded success of the VPP. This means thatventricular pacing will not be provided asynchronously, as was a defaultin previous devices during noise situations. During this period ofnoise, the IMD 10 is unable to accurately sense intrinsic ventricularactivity. As indicated, the duration of the noise is typically short andthus, this poses little risk to the patient. The benefit is that nounnecessary ventricular pacing is provided.

Conversely, if the patient is labeled as blocked (160), thenasynchronous pacing (170) is provided. It should be appreciated that apatient labeled as blocked may have their IMD 10 operate in DDD/R mode asubstantial period of the time. Thus, the noise response is consistentwith that in the DDD/R mode. Alternatively, a patient labeled as blocked(e.g., requiring ventricular pacing 85% of the time) may be operating inan atrial based mode (hence ventricular pacing is not required) at thetime noise is detected. Asynchronous pacing (170) is still provided dueto the high likelihood of a need for ventricular pacing when the deviceis unable to accurately sense.

As previously indicated, most patients will have data at one extreme orthe other making classification relatively easy. Those patients withinthe definable margins are likewise reliably classified. Those who areclassified as intermediate (e.g., 20%-80% ventricular pacing) will berare but pose a greater challenge. The indicated response forintermediate patients in the presence of noise is to follow theprogrammed option 190. Thus, the physician or caregiver may program thedesired action (e.g., whether or not to provide asynchronous pacingduring noise) for intermediate classifications. A conservative defaultmay be to treat intermediate patients as blocked (effectively removingthis as a classification and expanding the range of what is consideredblocked). Alternatively, further subclassifications may be provided,e.g., when ventricular pacing is occurring in 20%-40% treat theintermediate classification as intact. Another variable may be recenttrend data. For example, overall a patient may have ventricular pacing30% of the time; however, in the last four hours, the percentage hasbeen less than 10%. Thus, that provides a basis to inhibit asynchronouspacing (150) rather than pace for this intermediate patient. Anotheralternative used alone or in combination is to treat certainintermediate patients as intact for a limited amount of time. Forexample, if the noise duration extends for longer than X seconds or Ycardiac cycles, then the intermediate classification is considered to beblock. As should be appreciated, the time frames and requirements forthese types of sub-classifications may vary dramatically and could beprogrammed with specificity.

During the duration of the noise, the appropriate action is taken (150,170, 190). When noise is no longer an issue (130), the process returnsto normal operation in the VPP 100.

The atrial classifications are indicated in parenthesis in FIG. 2. Itshould be appreciated that the atrial and ventricular classificationsare separate and distinct. That is, a given patient may have intact AVconduction (as used herein) but may be classified as dependent foratrial pacing. Thus, the flowchart of FIG. 2 illustrates two separateprocesses that are presented together for brevity and clarity.

FIG. 3 is a table that sets out the various conditions and responses forthe atrial and ventricular responses, based upon classificationaccording to the present invention. As indicated, when the atrialchamber (or atrium) is classified as dependant and the ventricularchamber is classified as intact, the response during noise is to operatein an AOO mode. That is, asynchronous pacing is provided in the atriumbut inhibited in the ventricle. When the atrial chamber is reliable andthe ventricular chamber is blocked, the noise response is to operate inVOO. That is, atrial asynchronous pacing is inhibited and ventricularasynchronous pacing is provided. Finally, when the atrial chamber isdependant and the ventricular chamber is blocked, the noise response isoperation in a DOO mode where asynchronous pacing is provided in boththe atrium and ventricle.

There are various sources and types of noise that a patient mayencounter. Through shielding, circuit design, and various noisealgorithms, the vast majority of this noise will not interfere withnormal operation of the IMD 10. That is, merely because the patient isin a noisy environment does not mean that the IMD 10 will be affected bythat noise. It is only when the IMD 10 is actually affected by noise andrecognizes the same that these responses are taken. Most types of noisewill have a short duration, as explained previously. Some types of noisewill have an expected longer duration.

One example of noise having an expected longer duration is the fieldgenerated during an MRI. The MRI field may have a variety of effects onthe IMD 10 beyond generating noise that precludes accurate sensing. Forexample, currents may be induced in some leads that result in either astimulation of the patient, a pulse directed towards the circuitry,and/or heating of the components and hence the surrounding tissue. Thus,noise detection module 26 may include a specific MRI detection module(not separately shown) to identify that the IMD 10 is in an MRI field. Avariety of methods to detect the MRI field are known, such as sensingthe presence of a strong magnetic field.

With previous devices, the patient would have their IMD 10 programmed toan MRI safe setting some time prior to a scheduled MRI. This may requireoperation in this setting for many days or even weeks as scheduling maybe difficult. Thus, if the VPP is disabled in anticipation of an MRI,that patient loses the benefit provided by a reduction in pacing overthat time period. Of course, there may be a similar delay following theMRI before the patient may have the device programmed to the previoussettings. This results from the fact that in most MRI settings, neitherthe equipment nor the proper medical practitioners are readily availableto program the device. In an emergency setting, the MRI may beadministered without knowledge of the device, with knowledge of thedevice and a calculation of the risk, or the MRI may be delayed untilthe IMD 10 is programmed to an MRI safe setting.

The present invention functions as described above, even when MRI is theknown source of the detected noise. This provides a benefit to thepatient in that the VPP operates up until and right after the MRIsession, thereby reducing pacing over a longer duration. For thosepatients that require asynchronous pacing, this is again only providedover the duration required. In both cases, this reduces patient burden(in scheduling multiple appointments), avoids potentialerrors/oversights, and reduces clinician burden in reducing officevisits that only occur for MRI programming.

FIG. 4 is a flowchart illustrating a process for identifying anappropriate atrial capture management method. The IMD 10 operates 200according to the VPP, such as for example, the MVP™ mode. As describedabove, the IMD 10 records (210) data and classifies (220) the patientstatus. At various times, the IMD 10 will perform threshold testing todetermine the proper thresholds for pacing. The goal is to determine theappropriate pacing pulse levels (e.g., magnitude, duration) to assurecapture (with a safety margin in some cases) while minimizing powerconsumption. When done for atrial pacing, this is referred to as atrialcapture management (ACM) and may take two forms. The first is referredto as the AV conduction method. Here, an atrial pace is deliveredknowing, in advance, that AV conduction is intact. The ventricularchannel is monitored and if ventricular depolarization occurs within anexpected interval following the atrial pace, the atrial pace isdetermined to have captured. If the ventricular event fails to occur oroccurs outside this window (underlying ventricular rate or intrinsicatrial event occurs after the pace), then the atrial pace is determinedto be below threshold and hence did not capture the atrium. Levels areadjusted and this test is repeated until capture is reliably determined.

The other method of ACM is referred to as atrial chamber reset (ACR).This is used when AV conduction is not reliable or complete block ispresent. In this method, atrial timing is monitored. Prior to anexpected atrial event (e.g., based on rate), an atrial pacing pulse isdelivered. If this pulse captures the atrium, then the expected atrialevent is inhibited. Conversely, if the atrial pacing pulse fails tocapture, the expected atrial event occurs. This method is somewhat moredifficult to conduct as pacing and sensing occur on the same channel.

Furthermore, this necessitates at least a minor change in timing due tothe early delivery of atrial pacing pulses.

Thus, with the VPP in operation, the IMD 10 determines the type of ACMto employ (230) based upon the determined classification. If the patientis intact (240), then the AV conduction method (250) is utilized. Inorder to be classified as intact, the patient must have intrinsic AVconduction in a large percentage of cardiac cycles; thus, conduction isreliable and this type of ACM may be performed (the specific valuesemployed may be the same as the determination f for noise purposes, aspreviously discussed, or programmed to different values). As indicated,this type of ACM is preferable in that it does not deliver early atrialpacing pulse and monitors for capture on a separate channel from thatdelivering pacing. The present invention provides a relatively simpleautomated mechanism to determine which methodology to employ. As anexample, a patient having a previous device operating in DDD/R may havecompletely intact conduction; however, the DDD/R mode virtually assuresventricular pacing and makes a determination of AV conduction ratherdifficult.

Conversely, when classified as blocked (260), the IMD 10 will performACM using (270) the ACR method. This method is selected because thisclassification of patient does not have sufficiently reliably AVconduction to facilitate the AV conduction method of ACM. Thus, whilethe AV conduction method is preferable to ACR, ACR is preferable to notperforming conduction check and can be successfully used to determinethresholds.

Again, the intermediate classification (280) is unlikely; however, thetype of ACM employed may be a programmable option (290). The same typesof variations discussed above with respect to noise are applicable here.Certainly patients near the threshold values for intact classificationsmay benefit from an attempt to utilize the AV conduction method. Inanother embodiment, an attempt is made to utilize the AV conductionmethod for all intermediate patients. If successful, then this method isused again. If unsuccessful, ACR is utilized and becomes the defaultuntil or unless the patient classification changes.

1. An implantable medical device (IMD) comprising: means for operating the IMD with a Ventricular Pacing Protocol (VPP); means for providing cardiac pacing; means for selectively operating the IMD to inhibit or provide asynchronous pacing when noise is detected by the IMD, based upon a patient classification.
 2. The IMD of claim 1, further comprising: means for recording data regarding ventricular pacing during operation of the IMD with the VPP.
 3. The IMD of claim 2, further comprising: means for classifying a patient based upon the recorded data.
 4. The IMD of claim 3, wherein the means for classifying classify the patient based upon a percentage of cardiac cycles requiring ventricular pacing into a first classification and a second classification, wherein the first classification includes a lower percentage of ventricular pacing than the second classification.
 5. The IMD of claim 4, wherein the IMD inhibits asynchronous pacing when noise is detected and the means for classifying indicate the first classification and the IMD provides asynchronous pacing when noise is detected and the means for classifying indicate the second classification.
 6. The IMD of claim 4, further comprising: means for selecting a first atrial capture management (ACM) algorithm for when the means for classifying indicate the first classification and selecting a second ACM algorithm when the means for classifying indicate the second classification.
 7. The IMD of claim 6, wherein the first ACM algorithm is an AV conduction algorithm and the second ACM algorithm is an atrial chamber reset algorithm.
 8. A method comprising: operating an implantable medical device (IMD) having pacing capabilities according to a Ventricular Pacing Protocol (VPP); classifying an AV conduction status based upon the performance of the IMD while operating according to the VPP, wherein the status is a first classification or a second classification and an occurrence of ventricular pacing is lower for the first classification than for the second classification; determining the presence of a condition allowing for the selection of a first response or a second response; and selecting the first response when the first classification indicates the AV conduction status and the second response when the second status indicates the AV conduction status.
 9. The method of claim 8, further comprising: recording data within a memory of the IDM indicative of ventricular pacing during operation according to the VPP, wherein classifying the AV conduction status occurs based upon the recorded data.
 10. The method of claim 8, wherein the condition is presence of noise detected by the IDM.
 11. The method of claim 10, wherein the first response is inhibition of pacing and the second response is delivering asynchronous pacing.
 12. The method of claim 11, wherein the first classification includes ventricular pacing in 10% or less of a total number of cardiac cycles operated according to the VPP.
 13. The method of claim 11, wherein the first classification includes ventricular pacing in 20% or less of a total number of cardiac cycles operated according to the VPP.
 14. The method of claim 8, wherein the condition is the selective performance of an atrial capture management (ACM) test.
 15. The method of claim 14, wherein the first response is performing ACM utilizing AV conduction methodology and the second response is performing ACM using an atrial chamber reset (ACR) methodology.
 16. The method of claim 15, wherein the first classification includes ventricular pacing in 10% or less of a total number of cardiac cycles operated according to the VPP.
 17. The method of claim 15, wherein the first classification includes ventricular pacing in 20% or less of a total number of cardiac cycles operated according to the VPP.
 18. A method comprising: operating an implantable medical device (IMD) according to a Ventricular Pacing Protocol (VPP) which causes the IMD to operate in an atrial based pacing mode and monitor for intrinsic AV conduction over an entire cardiac cycle and provide ventricular backup pacing in a cardiac cycle subsequent to a first cardiac cycle devoid of sensed ventricular activity, operate in a dual chamber based pacing mode upon a detected loss of AV conduction satisfying VPP criteria, and periodically performing conduction checks during operation in the dual chamber based pacing mode; monitoring the operation of the IMD and recording data indicative of the occurrence of ventricular pacing; classifying an AV conduction status based upon the data, wherein a first status is indicative of a lower occurrence of ventricular pacing than a second status; monitoring for the presence of noise; providing asynchronous pacing if noise is detected and the AV Conduction status is classified as the second status; and inhibiting asynchronous pacing if noise is detected and the AV conduction statues is classified as the first status. 